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. Author manuscript; available in PMC: 2014 Jun 16.
Published in final edited form as: Biotechnol Prog. 2007 Dec 4;24(1):29–37. doi: 10.1021/bp070120b

Figure 6.

Figure 6

Effect of inhibition of SucDH. Sodium malonate dihydrate (Mal, 5–50 mM) and carboxin (Cbxn, 50–500 uM) were used for inhibitors. (a) On cytotoxicity. LDH release was reduced significantly in palmitate (Palm, P) cultured cells by both inhibitors on day 1. (b) On the release of B–OH by the cells. Carboxin reduced BOH significantly and malonate reduced BOH to basal level in palmitate cultured cells on day 1. Data presented as average ± SD of 6 replicates from two independent experiments. * denotes significance with p < 0.01 with Student’s t-test.