Table 4.

MNI Coordinates of Clusters of Significant (P < .025, Family Wise Error Corrected, One-Sided) Group Difference in MD and RD (CHR > Controls)

Diffusion Tensor Imaging Index	Cluster Size (mm2)	MNI Coordinates of Peak Voxel			White Matter Tracts Overlapping With the Clusters (Size of Overlap in mm3)a
		X	Y	Z
MD	9 169	24	−50	20	r SLF (703), r PCR (501), splenium of corpus callosum (409), r PLIC (322), r SCR (240), r cerebral peduncle (161), r RLIC (158), r cingulum (cingulate part, 130), body of corpus callosum (125), r PTR (69), r ALIC (50), r fornix/stria terminalis (38), r EC (16), r tapetum (2)
	5	12	−26	71
	2	24	29	35
	1	29	50	25
RD	52	31	−51	22	r PCR (51)
	8	32	−53	26

Note: Abbreviations are explained in the first footnote to table 2. MNI, Montreal Neurological Institute; MD, mean diffusivity; RD, radial diffusivity; PLIC, posterior limb of internal capsule; SCR, superior corona radiata; RLIC, retrolenticular part of internal capsule; ALIC, anterior limb of internal capsule.

^aWhite matter tracts as defined with the Johns Hopkins University White Matter Label Atlas.²⁴