Table 2.
Results From the 16 C-phosphate-G Sites Associated With SZ
| Gene | Target ID | Discovery | Validation | Gene expression | Reality Distortion Symptoms | ||||
|---|---|---|---|---|---|---|---|---|---|
| Δβa | P value | Δβa | P value | Δb | P value | r c | P value | ||
| CD244 | cg11939496 | −0.03 | 4.75E-05 | −0.04 | 6.47E-10 | −0.07 | 1.91E-02 | 0.26 | 8.50E-03 |
| LAX1 | cg12022621 | 0.02 | 4.04E-05 | 0.01 | 6.18E-02* | −0.10 | 5.67E-03 | −0.26 | 1.06E-02 |
| ESPNL | cg09039163 | −0.03 | 1.28E-05 | −0.01 | 2.52E-03 | −0.02 | 5.47E-02 | 0.11 | 2.84E-01 |
| TXK | cg20981615 | 0.03 | 3.36E-05 | 0.01 | 1.24E-04 | 0.02 | 3.34E-01 | −0.36 | 3.00E-04 |
| PRF1 | cg09914304 | 0.02 | 2.50E-05 | 0.04 | 3.69E-07 | −0.46 | 2.29E-10 | −0.20 | 4.47E-02 |
| MS4A1 | cg06806711 | 0.02 | 9.26E-06 | 0.01 | 6.10E-04 | 0.02 | 3.78E-01 | −0.15 | 1.27E-01 |
| TCN1 | cg20018806 | −0.02 | 3.65E-05 | −0.01 | 1.20E-04 | 0.23 | 2.23E-03 | 0.22 | 2.84E-02 |
| APBA2 | cg21917349 | 0.03 | 3.64E-05 | 0.01 | 1.67E-02 | −0.01 | 9.11E-01 | −0.27 | 6.50E-03 |
| FAM173A | cg09830866 | 0.03 | 9.66E-05 | 0.04 | 1.53E-07 | −0.08 | 2.72E-02 | −0.31 | 2.30E-03 |
| CBFA2T3 | cg13745346 | −0.02 | 1.11E-05 | −0.03 | 4.10E-07 | −0.09 | 1.93E-06 | 0.27 | 7.70E-03 |
| MPG | cg16003913 | −0.03 | 8.87E-05 | −0.01 | 5.89E-02* | 0.00 | 7.32E-01 | 0.31 | 1.60E-03 |
| CD7 | cg02473123 | 0.02 | 6.05E-05 | 0.02 | 1.11E-03 | −0.22 | 2.41E-05 | −0.22 | 2.76E-02 |
| MPO | cg04988978 | −0.03 | 9.15E-05 | −0.01 | 6.93E-05 | 0.08 | 2.54E-01 | 0.18 | 7.30E-02 |
| SLC25A10 | cg07845392 | −0.02 | 2.59E-05 | −0.04 | 9.50E-10 | 0.01 | 5.48E-01 | −0.03 | 7.51E-01 |
| CKM | cg19154438 | 0.02 | 3.33E-05 | 0.03 | 6.63E-09 | 0.00 | 4.75E-01 | −0.21 | 4.18E-02 |
| H1F0 | cg07141002 | −0.03 | 8.38E-06 | −0.04 | 2.92E-06 | −0.08 | 1.22E-01 | 0.14 | 1.58E-01 |
aΔβ of SZ patients—controls.
bΔ, a gene expression difference of SZ patients—controls.
c r, correlation between reality distortion symptom scores and methylation values.
*Marginal significant P values of ~.06.