Table 2.

Genome-wide Association Study, Follow-up Study, and Meta-analysis Results on the Xq28 Chromosomal Region

Chromosome	Single nucleotide polymorphism	Location (bp)	Risk Allele	Stage 1: Genome-wide association study			Stage 2: Follow-up study			Meta-analysis		Gene
				OR	95% CI*	P Value	OR	95% CI*	P Value (1-tailed)	OR	P Value
X	rs2269368	152843013	C	1.40	1.21–1.62	3.92×10−5	1.18	1.06–1.32	.0014	1.253	4.74×10−7	ARHGAP4
X	rs2269372	152860739	A	1.62	1.39–1.90	2.84×10−6	1.16	1.02–1.31	.0102	1.313	3.98×10−8	RENBP
X	rs2734647	152945374	C	1.51	1.29–1.78	2.39×10−5	1.15	1.02–1.30	.0107	1.275	8.78×10−7	MECP2
X	rs2239464	153001625	G	1.55	1.31–1.83	2.71×10−6	1.12	0.98–1.27	.0456	1.261	6.71×10−6	MECP2

Note: *95% Confidence interval (CI) of the odds ratio (OR).