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. 2014 Jun 7;14:47. doi: 10.1186/1475-2867-14-47

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Copyright © 2014 Cui et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The effect of hsa-miR-574-5p antisense and miRNA mimics transfection on MACC-1 expression in SW1116 and HCT116 cell lines. A&B. Effect of hsa-miR-574-5p on MACC-1 expression in HCT116 and SW1116 cells; compared with control group, mimic group reduced MACC-1 expression, while inhibitor group increased MACC-1 expression (*P < 0.05, inhibitor vs. control group; ^#P < 0.05, mimic vs. control group; ^★P < 0.01, mimic vs. control group); C. hsa-miR-574-5p expression was reduced in antisense (inhibitor group) transfected HCT116 cells, while it was increased in miRNA mimics (mimic group) transfected SW1116 cells (^#P < 0.01 vs. control group).