Table 2.
Characteristics, clinical signs, case classifications and rubella antibodies among seven confirmed or potential CRS cases
| Cases | Age (months) | Clinical signs | WHO definitions for CRS cases | IgM (OF) | IgM (DBS) | IgG (DBS) | History of Maternal rash |
|---|---|---|---|---|---|---|---|
| Case 1 |
3 |
Glaucoma |
Congenital rubella infection |
+ |
+ |
NT |
No |
| Case 2 |
9 |
Cataract, pigmentary retinopathy, microphthalmia |
Laboratory-confirmed CRS |
+ |
+ |
+ |
No |
| Case 3 |
6 |
Cataract, CHD (VSD), splenomegaly, jaundice |
Clinically-confirmed CRS# |
– |
– |
+ |
Yes |
| Case 4 |
6 |
Glaucoma, CHD (PDA, ASD) |
Clinically-confirmed CRS# |
– |
± |
+ |
No |
| Case 5 |
6 |
Pigmentary retinopathy |
Suspected CRS# |
– |
– |
+ |
No |
| Case 6 |
6 |
Cataract |
Suspected CRS# |
– |
– |
+ |
No |
| Case 7 | 12 | Micropthalmia, purpura | Suspected CRS# | – | – | + | No |
ASD = atreial septal defect; CHD = congenital heart disease; NT = Not Tested; PDA = Patent ductus arteriosus; VSD = Ventricular septal defect; # = potential CRS case.