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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Neurobiol Dis. 2014 Apr 12;67:140–148. doi: 10.1016/j.nbd.2014.03.020

Figure 1. The cerebellum contributes to the stiff-legged dystonic gait of Atcayji-hes mice.

Figure 1

A. Footprint pattern of Atcayji-hes mice and littermate controls. B. Atcayji-hes mice exhibit reduced stride length with a normal base width. C. Atcayji-hes mice exhibit significantly abnormal foot placement and have impaired performance on the rotarod (D). E.. Atcayji-hes mice have a stiff legged gait with abnormal hind limb extension F. Following a partial cerebellectomy, the same mouse has a broad-based ataxic gait without hind limb extension during gait (n = 4 mice). G. The site of the cerebellar lesion involving the DCN and overlying cerebellar cortex is shown (n = 4 mice). Arrow: DCN, Arrowheads: Cerebellar cortical destruction. Data in each graph are presented as mean ± SEM.