Figure 2.
Acute pulmonary effects of CeO2 nanoparticles in C57BL/6 mice. The dose-dependent experiment was carried out in mice exposed to CeO2 nanoparticles C5 at 0.5, 1.0, 2.0 and 4.0 mg/kg by oropharyngeal aspiration. There were 6 animals per group. Animals were euthanized after 40 hr, and BALF was collected to determine neutrophil cell counts (A), LIX (B) and IL-1β (C) levels. Animals exposed to 5.0 mg/kg QTZ were used as positive control. The experiment was reproduced a second time; * p < 0.05 compared to control; # p < 0.05 for pairwise comparisons as shown.