Table 3. Subsequent embryonic development of immature COCs matured in IVM-medium without rh-AMH (Control) or with 100 ng/ml rh-AMH, AdH1-SiRNA/NS, AdH1-SiRNA/AMH respectively and followed by in vitro fertilization (IVF).
Group of treatment | No. of COCs examined | No. of 2-cell embryos developed (%) | No. of blastocysts developed (%) |
Control | 157 | 120 (76.4±5.4) | 38 (31.7±2.7) |
rh-AMH | 150 | 120 (80.0±4.5) | 48 (40.0±3.3)* |
AdH1-SiRNA/NS | 142 | 103 (73.1±8.9) | 35 (33.9±5.9) |
AdH1-SiRNA/AMH | 135 | 95 (70.3±5.9) | 20 (20.6±2.9)** |
Data showed 3 replicates.
*Indicates significant difference compared to control group (P<0.05);
**indicates significant difference compared to AdH1-SiRNA/NS group (P<0.05).