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. 2014 Jun 16;9(6):e99393. doi: 10.1371/journal.pone.0099393

Table 3. Subsequent embryonic development of immature COCs matured in IVM-medium without rh-AMH (Control) or with 100 ng/ml rh-AMH, AdH1-SiRNA/NS, AdH1-SiRNA/AMH respectively and followed by in vitro fertilization (IVF).

Group of treatment No. of COCs examined No. of 2-cell embryos developed (%) No. of blastocysts developed (%)
Control 157 120 (76.4±5.4) 38 (31.7±2.7)
rh-AMH 150 120 (80.0±4.5) 48 (40.0±3.3)*
AdH1-SiRNA/NS 142 103 (73.1±8.9) 35 (33.9±5.9)
AdH1-SiRNA/AMH 135 95 (70.3±5.9) 20 (20.6±2.9)**

Data showed 3 replicates.

*Indicates significant difference compared to control group (P<0.05);

**indicates significant difference compared to AdH1-SiRNA/NS group (P<0.05).