Table 4. Correlations between questionnaire scores and the absolute post-DST cortisol deviation among bipolar patients.
Pearson correlations (n = 145) | ||
r | p | |
Depression | ||
BDI | 0.228 | 0.006 |
MADRS-S | 0.229 | 0.006 |
Anxiety | ||
BAI | 0.129 | 0.122 |
BSA-S | 0.170 | 0.041 |
Global Functioninga | ||
GAF current | −0.145 | 0.085 |
GAF last year | −0.228 | 0.006 |
Quality of Lifeb | ||
Overall QOL | −0.229 | 0.006 |
Physical domain | −0.202 | 0.015 |
Psychological domain | −0.241 | 0.004 |
Independence domain | −0.291 | <0.001 |
Social relationships domain | −0.116 | 0.167 |
Environment domain | −0.215 | 0.010 |
Spirituality domain | −0.170 | 0.041 |
BAI, Beck Anxiety Inventory; BSA-S, Brief Scale for Anxiety – Self assessment; BDI, Beck Depression Inventory; DST, dexamethasone suppression test; GAF, Global Assessment of Functioning; MADRS-S, Montgomery Åsberg Depression Rating Scale – Self assessment; QOL, Quality of Life. We aimed to evaluate whether the magnitude of the deviation from an “ideal” post-DST cortisol value within the patient sample was positively correlated with more symptoms, lower global functioning and QOL (for a more detailed explanation see the results and discussion sections). To that effect, we chose the median post-DST cortisol value within the control group as an “ideal” value (308 nmol/l) and the absolute post-DST cortisol deviation from that value was calculated for each patient. Bivariate correlations were performed using Pearson correlation.
Global Functioning analyses, n = 142.
Quality of Life analyses, n = 144.