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. 2014 Jun 16;9(6):e98682. doi: 10.1371/journal.pone.0098682

Table 4. Correlations between questionnaire scores and the absolute post-DST cortisol deviation among bipolar patients.

Pearson correlations (n = 145)
r p
Depression
BDI 0.228 0.006
MADRS-S 0.229 0.006
Anxiety
BAI 0.129 0.122
BSA-S 0.170 0.041
Global Functioninga
GAF current −0.145 0.085
GAF last year −0.228 0.006
Quality of Lifeb
Overall QOL −0.229 0.006
Physical domain −0.202 0.015
Psychological domain −0.241 0.004
Independence domain −0.291 <0.001
Social relationships domain −0.116 0.167
Environment domain −0.215 0.010
Spirituality domain −0.170 0.041

BAI, Beck Anxiety Inventory; BSA-S, Brief Scale for Anxiety – Self assessment; BDI, Beck Depression Inventory; DST, dexamethasone suppression test; GAF, Global Assessment of Functioning; MADRS-S, Montgomery Åsberg Depression Rating Scale – Self assessment; QOL, Quality of Life. We aimed to evaluate whether the magnitude of the deviation from an “ideal” post-DST cortisol value within the patient sample was positively correlated with more symptoms, lower global functioning and QOL (for a more detailed explanation see the results and discussion sections). To that effect, we chose the median post-DST cortisol value within the control group as an “ideal” value (308 nmol/l) and the absolute post-DST cortisol deviation from that value was calculated for each patient. Bivariate correlations were performed using Pearson correlation.

a

Global Functioning analyses, n = 142.

b

Quality of Life analyses, n = 144.