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. 2014 Jun 16;9(6):e96443. doi: 10.1371/journal.pone.0096443

Figure 11. Depicted above are: the variations in TDMI for insulin secretion, Inline graphic, and kidney/liver function, Inline graphic, when varied by up to Inline graphic of their nominal values.

Figure 11

Note that both undergo at least one bifurcation (qualitative state change) over this variation in parameters.