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. 2014 Jun 16;9(6):e99490. doi: 10.1371/journal.pone.0099490

Table 1. Univariate analysis of prognostic factors for OS and EFS in medulloblastoma patients (n = 173).

Factors No. of cases 5-year OS(%) p-value 5-year EFS(%) p-value
Sex
Male 112 49.8 0.216 43.2 0.384
Female 61 55.5 48.6
Age
Children 118 47.6 0.090 41.9 0.047
Adult 55 62.7 51.7
Location
Midline 152 50.2 0.219 43.7 0.228
Lateral 21 65.3 54.9
Involvementa
Yes 63 43.3 0.002 35.2 0.001
No 84 63.8 55.2
Unknown 26
Tumor Size
<3 cm 110 56.8 0.314 47.7 0.444
≥3 cm 37 44.2 41.8
Unknown 26
Extent of resection
Gross total 114 60.9 0.002 53.9 <0.001
Subtotal 52 42.7 33.0
Unknown 7
CSF Shunting
Yes 53 45.8 0.074 41.1 0.055
No 103 56.0 47.5
Unknown 17
RTb
Yes 139 58.4 <0.001 49.3 <0.001
No 34 8.0 8.0
CHTc
Yes 98 62.1 <0.001 51.2 0.001
No 75 38.9 38.9
Institution
A 153 53.3 0.184 46.9 0.238
B 20 40.0 40.0
a

involving brain stem or IV ventricle floor by the tumor.

b

indicating postoperative primary radiation therapy.

c

indicating postoperative primary chemotherapy.

Institution A =  Huashan Hospital.

Institution B = Southwest Hospital.