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. 2014 Jun 16;9(6):e99490. doi: 10.1371/journal.pone.0099490

Table 3. Univariate analysis of histological and molecular subgroups for OS and EFS in medulloblastoma patients (n = 173).

Factors No. of cases 5-year OS(%) p-value 5-year EFS(%) p-value
Histological subgroups
CMB 119 51.7 0.187 46.7 0.643
DMB 45 61.0 45.7
AMB 9 18.5 18.5
Molecular subgroups
SHH 40 50.4 0.182 40.9 0.277
WNT 37 69.2 59.2
Non-SHH/WNT 96 45.9 41.0
Molecular subgroupsa
WNT 30 83.3 0.028 78.6 0.081
Other 118 54.9 44.6

CMB = Classic medulloblastoma, DMB = Desmoplastic/nodular medulloblastoma, AMB = Large-cell/anaplastic medulloblastoma, SHH = SHH pathway medulloblastoma, WNT = WNT pathway medulloblastoma, Non-SHH/WNT =  Non-SHH/WNT pathway medulloblastoma.

a

those patients who did not receive any adjuvant therapies after primary resection were excluded.