Table 1.
Characteristic | Mean (SD) | |
---|---|---|
Converters (n = 20) | Nonconverters (n = 82) | |
Age,b y | 78.1 (6.9) | 71.4 (5.9) |
Sex, No. | ||
Male | 4 | 29 |
Female | 16 | 53 |
Education, y | 12.1 (3.4) | 12.2 (4.7) |
MMSE score | 27.5 (2.5) | 28.2 (1.7) |
z Score | ||
Episodic | −0.16 (0.8) | 0.11 (0.8) |
Executive | −0.32 (0.5) | −0.02 (0.5) |
APOE4, % | 26 | 26 |
Observation interval, y | 4.4 (2.1) | 3.8 (2.3) |
Time to convert, y | 3.0 (1.9) |
Abbreviation: MMSE, Mini-Mental State Examination.
Of 102 participants who were cognitively normal at baseline, 20 subsequently progressed (“converted”) to mild cognitive impairment (18 participants) or Alzheimer disease (2 participants), and 82 remained normal throughout the time frame of our study.
Significant difference.