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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: J Neurooncol. 2014 Mar 26;118(1):83–92. doi: 10.1007/s11060-014-1422-5

Figure 3. The drug combination with radiation further decreases MPNST cell proliferation.

Figure 3

(A) MPNST cells were subjected to radiation (4 Gy) Gammacell 1000 (2.24 Gy/min; radiation source: Caesium137), treated with bortezomib (5 nM) plus rapamycin at 50% of IC50 (25 M for NF90.8; 21 M for T265-2C cells and 27 M for sNF96.2) or everolimus 50% of IC50 (10 M for NF90.8; 9.6 M for T265-2C cells and 11.8 M for sNF96.2) and after 96 hours cell growth was assessed by alamarBlue assay. (*) P < 0.05; (**) P < 0.01; (***) P < 0.0001.