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. Author manuscript; available in PMC: 2015 May 20.
Published in final edited form as: J Evol Biol. 2013 Dec 16;27(1):161–169. doi: 10.1111/jeb.12284

Figure 2. Selection strength of beneficial mutations and mutator dynamics in bottlenecked populations.

Figure 2

Bottlenecks inhibited mutator fixation across all parameter combinations simulated. The probability of fixation (circles) declined while the average time to fixation (squares) increased faster in populations with smaller mutations. Beneficial mutations were drawn from exponential distributions with means 0.05 (solid), 0.02 (dashed), or 0.01 (dotted). All populations were propagated at N = 106, while Ub varied between 10−6 (A), 10−7 (B), and 10−8 (C). The mutator increased the mutation rate 50-fold. Error bars on the time to fixation represent 1 standard deviation. Results are averaged over 1000 runs of the simulation.