TABLE V.

Independent prognostic factors by Cox modelling

Variable	Coefficient	hr	95% ci	p Value
afp group	0.575	1.777	1.297 to 2.437	<0.001
Sex	−0.0.87	0.917	0.759 to 1.717	0.366
Age	0.028	1.029	1.021 to 1.036	<0.001
Tumour size	0.003	1.003	0.989 to 1.017	0.656
Peritoneal seeding	0.628	1.874	1.490 to 2.356	<0.001
Liver metastasis	0.575	1.776	1.253 to 2.519	0.001
Lymph node metastasis	0.267	1.306	1.035 to 1.649	0.025
Lymphatic invasion	0.003	1.003	0.809 to 1.244	0.979
Vascular invasion	−0.313	0.731	0.550 to 0.974	0.032
TNM stage	0.417	1.518	1.310 to 1.759	<0.001
Curative surgery	0.265	1.304	1.054 to 1.612	0.015
Serosal invasion	0.356	1.427	1.142 to 1.783	0.002
Differentiation	0.070	1.073	0.928 to 1.240	0.343
Lauren classification	−0.122	0.885	0.789 to 0.992	0.037

hr = hazard ratio; ci = confidence interval; afp = alpha-fetoprotein.