Table 4. Regions of interest analysis of task familiarity effects.
| Component | Region | t | P (two tailed) |
|---|---|---|---|
| (a) Novel blocks>familiar blocks | |||
| C1 | Anterior lateral orbitofrontal cortex | 1.700 | 0.090 |
| C2 | Anterior insula/ inferior operculum | 5.230 | <0.001 |
| C3 | Superior frontal sulcus | 1.810 | 0.071 |
| C4 | Posterior lateral orbitofrontal cortex | 3.150 | 0.002 |
| C5 | Lateral frontal pole | 2.860 | 0.005 |
| C6 | Rostrolateral frontal cortex | 3.520 | <0.001 |
| C7 | Inferior frontal sulcus | 3.450 | <0.001 |
| (b) Familiarity × task interaction | |||
| C1 | Anterior lateral orbitofrontal cortex | 0.440 | 0.330 |
| C2 | Anterior insula/inferior operculum | 0.160 | 0.435 |
| C3 | Superior frontal sulcus | 0.810 | 0.210 |
| C4 | Posterior lateral orbitofrontal cortex | 0.630 | 0.266 |
| C5 | Lateral frontal pole | 1.010 | 0.157 |
| C6 | Rostrolateral frontal cortex | 0.390 | 0.350 |
| C7 | Inferior frontal sulcus | −0.570 | 0.716 |
| (c) Novel blocks>familiar blocks INHIBTION task only | |||
| C1 | Anterior lateral orbitofrontal cortex | −2.360 | 0.010 |
| C2 | Anterior insula/inferior operculum | −3.000 | 0.001 |
| C3 | Superior frontal sulcus | −1.630 | 0.053 |
| C4 | Posterior lateral orbitofrontal cortex | −0.990 | 0.161 |
| C5 | Lateral frontal pole | −2.380 | 0.009 |
| C6 | Rostrolateral frontal cortex | −3.180 | <0.001 |
| C7 | Inferior frontal sulcus | −3.480 | <0.001 |
N=16 participants with 4 × 4 conditions (task × familiarity). Results significant at P<0.05 are highlighted in bold.