Table 2.
Neuropathological spectrum of brain tumors in an European epilepsy surgery series
| Entity | Numbers (%) | Age OP | Onset | Duration |
|---|---|---|---|---|
| GG I° | 673 (43.3 %) | 24.9 | 12.8 | 12.7 |
| GG II°/III° | 77 (5.0 %) | 26.9 | 14.2 | 11.0 |
| DNET I° | 256 (16.5 %) | 25.2 | 14.7 | 10.7 |
| PXA | 38 (2.5 %) | 29.3 | 18.8 | 12.2 |
| INET | 29 (1.9 %) | 27.9 | 14.4 | 17.7 |
| SEGA | 16 (1.0 %) | 20.1 | 12.3 | 9.0 |
| ANET | 5 (0.3 %) | 19.7 | 2.0 | 13.0 |
| ASTRO II°/III° | 110 (7.1 %) | 36.2 | 29.5 | 6.7 |
| OLIGO II°/III° | 97 (6.3 %) | 38.6 | 24.5 | 12.5 |
| PA I° | 81 (5.2 %) | 25.1 | 14.8 | 12.1 |
| CYSTS | 31 (2.0 %) | 32.4 | 21.7 | 11.6 |
| MENINGIOMA | 26 (1.7 %) | 46.5 | 38.9 | 8.4 |
| NOS$ | 62 (3.2 %) | 29.2 | 16.1 | 13.3 |
| OTHER§ | 50 (4.0 %) | 31.5 | 25.0 | 11.3 |
| Total | 1,551 | 27.9 | 16.5 | 11.7 |
Summary of 1,551 LEAT diagnosis collected by the EEBB (total n = 5,842); 709 female and 821 male patients were included. Grading according to WHO I°, II° or III° [50]
Age at operation (mean in years); Age at epilepsy onset (mean in years); Epilepsy duration (mean in years)
GG gangliogliomas, DNET dysembryoplastic neuroepithelial tumors, PXA pleomorphic xantoastrocytomas, INET isomorphic astrocytoma variants (analogous to WHO I°; [9, 10, 80]), SEGA subependymal giant cell astrocytomas, ANET angiocentric gliomas, ASTRO astrocytoma variants, OLIGO oligodendrogliomas including mixed gliomas, PA pilocytic astrocytomas, CYSTS arachnoid, dermoid or epidermoid cysts, NOS highly differentiated neuroepithelial tumors (not otherwise specified), Other all other tumors at rare frequency (<1 %)