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Plasma ghrelin responses to duodenal infusions of mixed lipids (Intralipid; slightly hypotonic), isocaloric glucose (5-fold hypertonic), and Intralipid rendered iso-osmotic with the glucose infusion by supplementation with nonabsorbable lactulose. Ghrelin suppression as reflected in GN and D-AUC3h covaried with the osmolarity of the infusions. *Significant between-condition differences (ANOVA P < 0.05) for individual time points.
