Table 1.

Characteristics of 744 adults overall and by presence or absence of hypertension in the Baltimore Longitudinal Study of Aging

Characteristic*		Entire group (n = 744)	With hypertension (n = 235)	Without hypertension (n = 509)	P†
Age, years, %	<50	15.5	20.0	5.5	<0.0001
	50–59	22.6	25.3	16.6
	60–69	26.5	25.2	29.4
	70–79	23.8	18.7	34.9
	≥80	11.7	10.8	13.6
Male gender, %		49.9	54.5	47.7	0.09
Race, white, %		65.7	55.7	70.3	<0.0001
Current smoking, %		4.6	4.6	4.5	0.92
Body mass index (kg/m2), %	<18.5	0.7	0.6	0.9	<0.0001
	18.5–24.9	34.8	40.3	23.0
	25.0–29.9	38.2	36.9	40.8
	≥30	26.3	22.2	35.3
Waist circumference, cm		92.0 (82.9, 100.4)	90.2 (81.2, 91.8)	95.4 (88.1, 97.3)	0.0008
Metabolic syndrome, %		25.4	37.5	16.7	<0.0001
On angiotensin receptor blockers, %		1.1	1.7	0.8	0.26
On angiotensin converting enzyme inhibitors, %		14.6	34.9	5.3	<0.0001
Serum fibroblast growth factor 21(pg/mL)		227 (127, 371)	269 (161, 457)	208 (117, 335)	<0.0001
Total cholesterol, mg/dL		193 (171, 216)	193 (173, 216)	192 (164, 216)	0.15
HDL cholesterol, mg/dL		55 (46, 68)	54 (47, 69)	56 (45, 66)	0.16
LDL cholesterol, mg/dL		115 (83, 138)	110 (90, 133)	117 (95, 139)	0.05
Triglycerides, mg/dL		89 (66, 123)	95 (69, 133)	87 (65, 119)	0.03
C-reactive protein, μg/mL		1.17 (0.75, 2.34)	1.25 (0.87, 2.51)	1.10 (0.64, 2.29)	0.17
Fasting plasma glucose, mg/dL, %	≤99	73.5	60.8	79.4	<0.0001
	100–125	23.1	33.2	18.5
	>125	3.4	6.0	2.1
Estimated glomerular filtration rate, mL/(min·1.73m2)		77.2 (64.4, 90.2)	72.6 (59.1, 85.6)	79.5 (65.9, 91.2)	<0.0001
Chronic kidney disease, %		19.2	26.4	15.9	0.0008
Diabetes, %		5.9	12.3	2.9	<0.0001

^*Values are median (25^th, 75^th percentile) for continuous variables, and % for categorical variables.

^†Kruskal Wallis test used for continuous variables, chi-square test used for categorical variables.