Table 3.
Studies investigating diagnostic value of miR-210
| First author | Publication year | Types of cancer | Types of sample | Negative controls | Sensitivity | Specificity |
|---|---|---|---|---|---|---|
| Wang [81] |
2009 |
Pancreatic cancer |
plasma |
Healthy controls |
53% |
78% |
| Xing [86] |
2010 |
Squamous cell LC |
sputum |
Healthy controls |
58% |
79% |
| Shen [94] |
2011 |
Lung cancer |
plasma |
Benign SPNs |
56% |
73% |
| Tan [95] |
2011 |
Squamous cell LC |
tissue |
Normal lung tissue |
Not provided |
Not provided |
| Ren [96] |
2012 |
Pancreatic cancer |
stool |
Healthy controls |
85% |
67% |
| Li [97] |
2013 |
NSCLC |
sputum |
Healthy controls |
Not provided |
Not provided |
| Li [98] |
2013 |
NSCLC |
serum |
Healthy controls |
79% |
74% |
| Zhao [99] |
2013 |
Renal cancer |
serum |
Healthy controls |
81% |
79% |
| Iwamoto [100] | 2014 | Renal cancer | serum | Healthy controls | 65% | 83% |
Abbreviations: LC lung cancer, NSCLC non-small cell lung cancer, SPN solitary pulmonary nodule.