Table 1.
Study and patient characteristics
| Author (Year) | Country | Study design | Recruitment setting | Sample size (numbers) | Mean age (SD) | % Female | JIA/JRA diagnosis |
Disease duration |
|---|---|---|---|---|---|---|---|---|
| Mean Year (SD) | ||||||||
| Zamir (1998) [7] |
Israel |
Case control |
Pediatric rheumatology clinic |
JRA: 16 |
12 (4) |
69 |
Olig: 4 |
4.5 (3.4) |
| Controls: 9 |
Poly: 12 |
|||||||
| Bloom (2002) [25] |
USA |
Case control |
Hasbro Children's Hospital, Pediatric Rheumatology Clinic |
JRA: 25 |
8.7 |
80 |
Syst: 5 |
3.1 (range: 0.2-5.5 ) |
| Controls: 45 |
Range: 6-12 |
Olig: 9 |
||||||
| Poly: 11 | ||||||||
| Palermo (2005) [26] |
USA |
Cross- sectional |
Outpatient pediatric rheumatology clinics (NS) |
JIA: 20 |
NR |
67 |
Syst: 2 |
4.49 (NR) |
| Olig: 5 | ||||||||
| Poly: 7 | ||||||||
| ERA: 2 | ||||||||
| NS: 4 | ||||||||
| Passarelli (2006) [27] |
Brazil |
Case-control |
NR |
JRA: 21 |
13 (2) |
57 |
Syst: 9 |
NR |
| Controls: 20 |
Poly: 12 |
|||||||
| Long (2008) [1] |
USA |
Cross sectional |
Four clinical sites during specialty care visits (NS) |
JIA: 30 |
Range: 8-12 |
56 |
Syst: 3 |
NR |
| Olig:21 | ||||||||
| Poly: 6 | ||||||||
| Ward (2008) [3] |
USA |
Cross sectional |
Children's Hospital and Regional Medical Centre- Paediatric Rheumatology Clinic |
JRA: 70 |
8.5 (1.9) |
84 |
Syst: 4 |
Inactive JRA: 3.8 (1.7) |
| Olig: 26 |
|
|||||||
| Poly: 40 |
Active JRA: 3.4 (3.0) |
|||||||
| Ward (2010) [28] |
USA |
Cross sectional |
Seattle Children's Hospital and University of Washington School of Nursing sleep laboratory |
JIA: 69 |
8.5 (1.9) |
84 |
Sys: 3 |
NR |
| Olig: 26 | ||||||||
| Poly: 40 | ||||||||
| Butbul Aviel (2011) [29] |
Canada |
Cross sectional |
The Hospital for Sick Children |
JIA: 92 |
12.7 (0.4) |
66 |
Syst: 28 |
NR |
| Olig: 31 | ||||||||
| Poly: 33 | ||||||||
| Ward (2011) [30] |
USA |
Case control |
Seattle Children's Hospital Paediatric Rheumatology Clinic |
JIA: 70 |
8.5 (1.9) |
76 |
Sys: 4 |
NR |
| Controls: 46 |
Olig: 26 |
|||||||
| Poly: 40 | ||||||||
| Bromberg (2012) [31] | USA | Cohort | Pediatric Rheumatology Clinic | JIA: 51 | 12.4 (2.8) | 65 | Poly: 51 | NR |
*Abbreviations: ERA enthesitis-related, JIA juvenile idiopathic arthritis, JRA juvenile rheumatoid arthritis, NS not specified, NR not reported, Olig oligoarticular, Pauc pauciarticular, Poly polyarticular, RCT randomized controlled trial, SD standard deviation, Sys systemic arthritis.