Table 3.

Metabolic data in two groups of NASH patients basal conditions (T0) and after 12 months of treatment with RA (T12).

Parameters	Group 1 T0	Group 1 T12	% variation	P	Group 2 T0	Group 2 T12	% variation	P
BMI	30 ± 1.86	30 ± 1.8	0	ns	28 ± 0.50	26 ± 0.50	9	0.005
Glucose	116 ± 10	105 ± 8.2	−10	0.05	99 ± 2.15	99 ± 2	0	ns
Insulin	18 ± 2.26	17 ± 3.77	−8	ns	23 ± 4.34	14 ± 1.9	−40	0.001
HOMA	5 ± 1	4.5 ± 1.0	−11	ns	5.97 ± 0.6	3.43 ± 0.5	−42	0.001
AST	40 ± 19	27 ± 7	−33	0.05	72 ± 31	41 ± 14	−42	0.01
ALT	40 ± 17	35 ± 10	−14	ns	72 ± 39	50 ± 9	−31	0.05
GGT	67 ± 31	43 ± 12	−35	0.05	101 ± 81	84 ± 75	−16	ns
Steatosis score	1.86 ± 0.90	1.8 ± 0.7	−0.01	ns	1.8 ± 0.8	1.2 ± 0.6	−33	0.01
NAS score	4.67 ± 1.5	3.6 ± 1.15	−29	ns	3.8 ± 1.5	2.5 ± 0.51	−70	0.001
Portal infiltration	1.33 ± 0.8	1.0 ± 0.2	−25	ns	1.2 ± 0.7	0.5 ± 0.3	−58	0.001
Fibrosis	1.35 ± 0.8	0.67 ± 0.5	−50	0.01	1.2 ± 0.7	0.5 ± 0.3	−60	0.001