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Daily rhythms in mRNA levels of clock genes in POMC neurons in the hypothalamus of EGFP-POMC mice maintained under L/D. A, Bmal1; B, Clock; C, Per1; D, Per2; E, Per3. Relative mRNA levels of various genes were calculated as in Figure 1. *, **, Significantly different (P < .05, .01) from the lowest value, as per one-way ANOVA with the Dunnett post hoc test. Black bar represents the dark period. Data are mean ± SEM of N = 5–6 animals per time point.
