Table 7.
Reported IC50 values (μg/mL) of selected P. bleo phytoconstituents on human cell lines [28].
| Compound | IC50 (μg/mL) of different cell lines | |||||
|---|---|---|---|---|---|---|
| KB | MCF7 | CasKi | HCT 116 | A549 | MRC-5 | |
| Dihydroactinidiolide | 6.7 | 30 | 40 | 5 | 97 | 91.3 |
| β-sitosterol | >100 | 72 | 62 | >100 | 78 | >100 |
| 2,4-ditertbutylphenol | 0.81 | 5.75 | 4.5 | 29 | 6 | 20 |
| α-tocopherol | 8 | 7.5 | 6 | 31 | 6 | 30.5 |
| Phytol | 7.1 | 34 | 18 | 100 | 31 | 74.1 |
| Mixture of sterols | >100 | >100 | >100 | >100 | >100 | >100 |
| Doxorubicin | 1.3 × 10−2 | 7.6 × 10−2 | 6.0 × 10−3 | 3.6 × 10−1 | 2.2 × 10−1 | 5.5 × 10−1 |
A549: human lung carcinoma cell line, CasKi: human cervical carcinoma cell Line, HCT116: human colon carcinoma cell Line, KB: human nasopharyngeal epidermoid carcinoma cell Line, MCF-7: hormone dependent breast carcinoma cell Line, MRC-5: normal human fibroblast cell Lines.