Table 2.

Some popularly used nonherbal therapeutic drugs for nonalcoholic steatohepatitis.

Category	Synthetic drug	References
Antiobesity drugs	Orlistat, sibutramine, mazindol	[40]
Antioxidants	Vitamin E, vitamin C, polyphenols (resveratrol, etc.)	[41]
Cytoprotective agents	Ursodeoxycholic acid, n-3 polyunsaturated fatty acids (EPA and DHA)	[42]
Insulin sensitizers	Metformin (biguanide), thiazolidines (pioglitazone, Rosiglitazone)	[43]
Lipid lowering drugs	Statins, fibrates, NPC1L1 inhibitors (ezetimibe)	[44]
RAS blockers	Angiotensin II receptor blockers, angiotensin-converting enzyme inhibitors, antialdosterone (spironolactone and eplerenone), renin inhibitor (aliskiren), incretin-related agents, GLP-1 agonists/analogs (exenatide and liraglutide), DPP-4 inhibitors (sitagliptin and vildagliptin)	[17]