Table 2.
Recent-onset rheumatoid arthritis patients in the Sherbrooke Early Undifferentiated PolyArthritis Cohort a
| Patient demographics ( N = 339) | Seronegative | Seropositive |
|---|---|---|
| Number of patients (%) |
166 (49%) |
173 (51%) |
| Average age, yr (range) |
54.2 (21 to 92) |
65.6 (19 to 87) |
| Females, n (%) |
107 (64) |
105 (61) |
| Symptom duration, yr |
0.44 |
0.45 |
| SE status, n |
120 |
132 |
| SE alleles = 0 |
75 |
43 |
| SE alleles = 1 |
44 |
59 |
| SE alleles = 2 |
1 |
30 |
| Mean DAS28-CRP (±SD) |
5.10 (1.47) |
5.04 (1.44) |
| Mean CRP mg/L (±SD) |
24.4 (33.9) |
26.6 (35.6) |
| Mean Sharp score erosions (±SD) |
2.9 (6.1) |
3.8 (7.0) |
| Mean Sharp score narrowing (±SD) |
3.4 (6.1) |
2.2 (4.1) |
| Tender joints |
10.4 |
9.8 |
| Swollen joints |
10.5 |
10.2 |
| Patient VAS score (100-mm scale) | 54.2 | 53.9 |
aCRP, C-reactive protein; DAS28-CRP, Disease Activity Score in 28 joints C-reactive protein; SE, Shared epitope; VAS, Visual Analogue Scale. Seronegative vs seropositive analysis: Symptom duration, P = 0.85; DAS28-CRP, P = 0.72; CRP, P = 0.56; Sharp score erosions, P = 0.28; Sharp score narrowing, P = 0.09.