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Plasma Klotho levels following an acute bout of exercise in young and old mice. Young (3–4 months old, n = 4) and aged (22–24 months old, n = 4) wild-type mice performed a single session of 45-min, 0° incline treadmill running. In both groups of animals, plasma Klotho levels increased significantly following an exercise bout. *denotes significantly different from pre-training values (within age group).
