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Dendrimer ABP favors the IL-10 over IL-12 production in MoDC. The ratio of IL-12 to IL-10 production in the presence or in the absence of ABP and LPS + IFN-γ +/− dendrimer ABP was calculated for Mo (A) and MoDC (B). When IL-10 levels were not detectable, detection limit (5 pg/mL) was chosen as the denominator of the ratio. ABP, aza-bis-phosphonate; IFN-γ, interferon-gamma; IL, interleukin; LPS, lipopolysaccharides; Mo, monocytes; MoDC, monocyte derived dendritic cells.
