Table 1.
Pregnancy classes of medications used to treat systemic sarcoidosis.
| Category | Systemic medication | Pregnancy class | |
|---|---|---|---|
| Corticosteroid | Prednisone | C | Risk cannot be ruled out |
| Methylprednisolone | C | Risk cannot be ruled out | |
|
| |||
| Antimetabolite | Methotrexate | X | Should not be used during pregnancy |
| Mycophenolate | D | Positive evidence of risk | |
| Azathioprine | D | Positive evidence of risk | |
|
| |||
| Calcineurin inhibitor | Cyclosporine | C | Risk cannot be ruled out |
|
| |||
| Monoclonal antibody | Infliximab | B | No evidence of risk in humans |
| Adalimumab | B | No evidence of risk in humans | |
| Etanercept | B | No evidence of risk in humans | |
|
| |||
| Alkylating agents | Chlorambucil | D | Positive evidence of risk |
| Cyclophosphamide | D | Positive evidence of risk | |