Table 3.
Comparison of disease activity and organ involvement among AAV diseases
|
EGPA |
GPA |
MPA/RLV |
Unclassifiable |
|
|---|---|---|---|---|
| (n = 14) | (n = 33) | (n = 78) | (n = 31) | |
| BVAS |
16.1 ± 7.7 |
19.9 ± 7.4 |
18.4 ± 7.3 |
12.1 ± 7.6 |
| General |
10 (71.4) |
23 (69.7) |
56 (71.8) |
29 (93.6) |
| Cutaneousa,b |
10 (71.4) |
3 (9.1) |
16 (20.5) |
10 (32.3) |
| Mucous membranes/eyes |
1 (7.1) |
8 (24.2) |
9 (11.5) |
2 (6.5) |
| Ear, nose, and throata,b,c |
6 (42.9) |
28 (84.9) |
7 (9.0) |
1 (3.2) |
| Chestc |
5 (35.7) |
22 (66.7) |
30 (38.5) |
6 (19.4) |
| Cardiovascular |
2 (14.3) |
4 (12.1) |
6 (7.7) |
0 (0) |
| Abdominal |
0 (0) |
1 (3.0) |
0 (0) |
1(3.2) |
| Renala,b |
2 (14.3) |
21 (63.6) |
71 (91.0) |
15 (48.4) |
| Nervous systema,b | 13 (92.9) | 14 (42.4) | 33 (42.3) | 15 (48.4) |
Values expressed as mean ± standard error or number (percentage). Disease activity and patterns of organ involvement were defined by the BVAS 2003 scoring system. AAV, antineutrophil cytoplasmic antibody-associated vasculitis; BVAS, Birmingham Vasculitis Activity Score; EGPA, eosinophilic granulomatosis with polyangiitis; GPA, granulomatosis with polyangiitis (Wegener’s granulomatosis); MPA, microscopic polyangiitis; RLV, renal-limited vasculitis. Comparisons between the EGPA, GPA, and MPV/RLV groups were made by Student t test or Mann–Whitney U test. Statistical significance was determined by P < 0.05/3 using Bonferroni correction: aEGPA versus GPA, bEGPA versus MPA/RLV, cGPA versus MPA/RLV. Unclassifiable AAV was not compared with other forms of AAV.