GLUT1 |
Many cell types (e.g., erythrocytes, brain); fetal tissues |
Basal glucose uptake; transport across blood-tissue barriers |
Rodents, humans, horses, cows, dogs, pigs |
GLUT2 |
Kidney, small intestine, liver, pancreatic islets, brain |
High-capacity low-affinity facilitated glucose and fructose transporter |
Rodents, humans, horses, cows |
GLUT3 |
Brain (neurons) and testis |
High-affinity facilitated glucose transporter; neuronal transport |
Rodents, humans, cows, dogs, pigs |
GLUT4 |
Striated muscle, fat, heart |
High-affinity facilitated glucose transporter; insulin-regulated transport; linked to IR/diabetes |
Rodents, humans, horses, cows, dogs, pigs |
GLUT5 |
Small intestine, kidney, striated muscle, fat, testis |
Facilitated fructose transporter |
Rodents, humans, horses, cows, dogs, pigs |
GLUT6 |
Leukocytes, brain, spleen |
Facilitated glucose transporter |
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GLUT7 |
Small intestine, colon, testis |
Transport of glucose and fructose |
|
GLUT8 |
Testis, brain, blastocyst, striated muscle, fat, liver, spleen, lung |
Facilitated glucose transporter widely expressed; neuronal transport; insulin-responsive transport in blastocyst |
Rodents, humans, cows, horses |
GLUT9 |
Liver, kidney, small intestine |
Facilitated urate (glucose) transporter |
Rodents, humans |
GLUT10 |
Striated muscle, lung, liver, pancreas |
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GLUT11 |
Striated muscle |
Muscle-specific; facilitated glucose/fructose transporter |
Rodents, humans |
GLUT12 |
Striated muscle, fat, prostate, mammary gland |
A second insulin-responsive facilitated GLUT? |
Rodents, humans, cows, horses |
HMIT |
Brain, fat |
H+/myo-inositol cotransporter |
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GLUT14 |
Testis |
Orphan transporter |
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