Fig. 1.

Rapid clearance of chronic LCMV infection in the presence of Fas-deficient DCs. Mice lacking Fas in DCs (B6.CD11c-Cre.FasKI, red dots) or in T cells (B6.Lck-Cre.FasKI, blue dots) and control (B6.FasKI, black dots) mice were infected with LCMV-clone 13 and viral titers were estimated by plaque assay in the spleens (A) and kidneys (B) of infected mice at the indicated timepoints after infection. Data are compiled from two independent experiments with 2–7 mice per time point. Dotted line indicates the limit of detection. Error bars represent SEM. Statistical significance was determined by ordinary one-way ANOVA (*P < 0.05; **P < 0.005; ns, not significant).