Fig. 4.

Biomechanical strength of fracture callus tissue. The maximum load sustained of fracture calluses (A) and contralateral tibias (B) from either alcohol or saline-exposed mice, with or without LiCl treatment at 14 days post-fracture. Alcohol exposure significantly reduced bending strength of fracture calluses and contralateral tibias compared with saline-exposed mice. LiCl partially restored fracture callus strength and significantly increased contralateral tibia strength in alcohol-exposed mice. Groups not sharing a letter are significant, P ≤ 0.05 using one-way ANOVA and Tukey's multiple comparison procedure. N = 14–18 mice/treatment group.