Table 4.
Optimal cutoff points with sensitivity and specificity, and area under the curve (AUC) for %dCDT, GGT and AST/ALT for three self-reported heavy alcohol use levels
| Optimal cutoff point | Sensitivity for optimal cutoff point (%) | Specificity for optimal cutoff point (%) | AUC | |
|---|---|---|---|---|
| Any heavy drinking | ||||
| %dCDT | 1.5% | 50.5 | 90.1 | 0.77 |
| GGT | 24 IU/l | 71.8 | 48.8 | 0.61 |
| AST/ALT | 1.08 | 56.1 | 59.0 | 0.59 |
| Recurrent heavy drinking | ||||
| %dCDT | 1.3% | 75.8 | 69.1 | 0.80 |
| GGT | 27 IU/l | 75.6 | 54.1 | 0.64 |
| AST/ALT | 1.08 | 60.2 | 56.3 | 0.59 |
| Persistent heavy drinking | ||||
| %dCDT | 1.4% | 81.4 | 69.7 | 0.81 |
| GGT | 40 IU/l | 55.2 | 70.3 | 0.66 |
| AST/ALT | 1.21 | 54.1 | 67.2 | 0.61 |
Any heavy drinking was defined as ≥4 drinks per occasion or >7 drinks per week for women, ≥5 drinks per occasion or >14 per week for men; Recurrent heavy drinking was defined as ≥5 drinks per day on at least 5 days over the past 30 days; Persistent heavy drinking was defined as ≥5 drinks per day on at least 7 consecutive days over the past 30 days.