Table 4.

Logistic regression models of associations between HLA sharing and preeclampsia among all subjects and stratified by sperm exposure

	All subjects		Low vaginal sperm exposuree		Normal to high vaginal sperm exposure
	OR	95% CI	OR	95% CI	OR	95% CI
Model 1a, b
HLA-A match	2.35	0.94, 5.86#	6.27	1.04, 37.97*	1.29	0.38, 4.42
HLA-B match	1.66	0.49, 5.65	f	--	1.16	0.27, 5.01
HLA-C match	1.22	0.54, 2.77	1.91	0.34, 16.29	1.14	0.40, 3.22
HLA-DRB1 match	0.70	0.23, 2.10	0.31	0.02, 2.87	0.78	0.19, 3.14
HLA-DQB1 match	1.65	0.69, 3.94	0.56	0.06, 2.52	3.22	1.04, 9.99*
Model 2a, c
# Class I matches	1.59	1.02, 2.47*	4.49	1.89, 14.50*	1.19	0.72, 1.08
# Class II matches	1.16	0.77, 1.73	0.49	0.20, 1.16	1.76	1.05, 2.98*
Model 3a, d
Total # matches	1.34	1.01, 1.79*	1.13	0.65, 1.96	1.45	1.02, 2.06*

^aAll models adjusted for pre-pregnancy BMI and maternal education and other HLA variables listed in the model

^bReference for each HLA gene match term is one match; all 5 HLA gene matching variables included in same model

^cNumber of Class I and II matches; Class I matches range from 3 to 6; Class II matches range from 2 to 5; OR for each one-match increase

^dTotal number of matches ranges from 5 to 10 matches; OR for each numerical match increase

^eLow sperm exposure is the lowest tertile of vaginal sperm exposure

^fOdds ratio could not be calculated because all who had complete matches for HLA-B were cases

^*p<0.05

^#p<0.10