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Transplantation of salivary gland stem cells rescues mice from radiation-induced hyposalivation. Salivary gland tissue is dispersed to a cell solution and allowed to form salispheres in culture. From these salispheres, c-Kit expressing stem cells are selected and injected into locally irradiated glands to improve saliva secretion [adapted from Gao et al. (75)]. n.d., not determined.
