Immunohistochemistry for doublecortin (DCX) in the dentate gyrus of (A, B) vehicle-, (C, D) C300-, (E, F) D-gal-, and (G, H) D-gal+C300-treated groups. Scale bar=50 μm (A, C, E, G); 25 μm (B, D, F, H). (I) The mean number of DCX-immunoreactive neuroblasts per section in all groups (n=5 per group; *P<.05, indicating a significant difference between vehicle/D-gal and C300/D-gal+C300; #P<.05, a significant difference between vehicle/C300 and D-gal/D-gal+C300). Error bar indicates SEM. Color images available online at www.liebertpub.com/jmf