FIG. 6.
Effects of proanthocyanidin administration on the expression of CYP2E1 in liver by immunohitochemical staining. At the completion of the experiment described in Figure 1, liver was harvested, and paraffin-embedded liver tissue from (A) control, (B) CCl4 control, and (C) CCl4+proanthocyanidins rats were stained with anti-CYP2E1 antibody and evaluated for CYP2E1 expression. Original magnification: 200×. (D) Changes in the cumulative value of optical density in immunohistochemical staining of CYP2E1. ##P<.01 compared to control; **P<.01, compared with CCl4 control. Color images available online at www.liebertpub.com/jmf