Mechanistic model of radiation response in head and neck cancer. (A) Radiation-sensitive SCC-61 and (B) Radiation-resistant rSCC-61. SM, sphingomyelin; GLUT, glucose transporter; FASN, fatty acid synthase; LDH, lactate dehydrogenase (A or B); MCT, monocarboxylate transporter. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars