Table 2.
N° | Sex |
Status |
Mucoid/non mucoid |
FEV1 |
FVC |
Total proteins |
IL-8 |
Flagellin |
---|---|---|---|---|---|---|---|---|
Stable/Exacerbation | (% pred.) | (% pred.) | (mg/ml) | (ng/100 μg prot) | (ng/100 μg protein) | |||
Patients with flagellin sputum < 10 ng/100 μg protein | ||||||||
3 |
M |
Stable |
Non mucoid |
24 |
55 |
6.58 |
3163.50 |
5.76 |
5 |
F |
Stable |
Non mucoid |
66 |
79 |
3.21 |
1680.15 |
4.80 |
6 |
F |
Exacerbation |
Mucoid |
64 |
73 |
4.57 |
2748.14 |
5.10 |
7 |
M |
Stable |
Non mucoid |
60 |
68 |
9.34 |
2548.47 |
5.62 |
8 |
M |
Exacerbation |
Non mucoid |
44 |
43 |
3.84 |
3064.52 |
2.92 |
11 |
F |
Stable |
Non mucoid |
91 |
106 |
3.15 |
1832.33 |
3.41 |
12 |
M |
Stable |
Non mucoid |
59 |
79 |
4.39 |
7971.28 |
2.68 |
13 |
M |
Stable |
Non mucoid |
44 |
60 |
11.8 |
5851.31 |
8.58 |
18 |
F |
Stable |
Non mucoid |
70 |
84 |
4.17 |
2289.97 |
3.62 |
20 |
M |
Stable |
Non mucoid |
43 |
58 |
8.68 |
2203.66 |
4.24 |
21 |
F |
Stable |
Mucoid |
43 |
58 |
5.91 |
3596.65 |
6.50 |
22 |
M |
Stable |
Non mucoid |
75 |
108 |
5.87 |
4286.10 |
3.82 |
24 |
M |
Stable |
Non mucoid |
46 |
74 |
7.25 |
3194.50 |
4.50 |
25 |
F |
Stable |
Non mucoid |
42 |
60 |
4.91 |
4089.03 |
3.68 |
31 |
M |
Stable |
Mucoid |
38 |
58 |
4.70 |
2681.30 |
7.17 |
34 |
F |
Exacerbation |
Non mucoid |
18 |
22 |
4.22 |
3050.02 |
1.74 |
35 |
F |
Stable |
Non mucoid |
41 |
54 |
7.83 |
1735.26 |
6.12 |
36 |
F |
Exacerbation |
Non mucoid |
41 |
61 |
6.71 |
3764.78 |
0.64 |
37 |
F |
Stable |
Mucoid |
57 |
82 |
8.93 |
4453.10 |
1.07 |
38 |
M |
Stable |
Non mucoid |
76 |
91 |
6.59 |
3437.08 |
2.73 |
Mean |
M: 50% |
|
non.mucoid:.80% |
52.10 |
68.65 |
6.13 |
3382.06 |
4.24 |
±SD |
|
|
18.11 |
20.39 |
2.30 |
1491.93 |
2.03 |
|
Patients with flagellin sputum > 10 ng/100 μg protein | ||||||||
2 |
F |
Stable |
Mucoid |
30 |
38 |
7.90 |
2189.72 |
11.23 |
4 |
F |
Stable |
Non mucoid |
66 |
81 |
3.25 |
1114.53 |
12.66 |
9 |
M |
Stable |
Mucoid |
20 |
39 |
8.22 |
1866.86 |
23.29 |
10 |
M |
Stable |
Mucoid |
40 |
62 |
4.11 |
4009.74 |
33.78 |
14 |
M |
Stable |
Non mucoid |
37 |
69 |
5.38 |
966.36 |
31.53 |
15 |
M |
Stable |
Non mucoid |
30 |
46 |
6.42 |
7007.48 |
13.40 |
16 |
F |
Exacerbation |
Non mucoid |
27 |
37 |
5.87 |
10848.53 |
60.65 |
17 |
M |
Stable |
Non mucoid |
29 |
57 |
2.79 |
2754.30 |
16.75 |
19 |
F |
Stable |
Non mucoid |
73 |
82 |
5.14 |
2142.72 |
30.01 |
23 |
F |
Stable |
Mucoid |
55 |
89 |
6.81 |
1648.29 |
13.88 |
26 |
M |
Stable |
Non mucoid |
55 |
55 |
8.44 |
3217.85 |
32.80 |
Mean |
M: 54.5% |
Non mucoid:.63.6% |
42.00 |
59.55 |
5.85 |
3433.31 |
25.45 |
|
±SD | 17.52 | 18.80 | 1.94 | 2981.86 | 14.65 |
Comparison of two groups of patients, a group with flagellin concentrations lower than 10 ng/100 μg proteins (20 patients), and a group with flagellin concentrations higher than 10 ng/100 μg proteins (11 patients).
FEV1 (% pred.) and FCV (% pred.) are forced expiratory volume in one second and forced vital capacity (expressed as percentage of the predicted value), respectively.