Table 6.
Body weight in MPS II (severe vs. attenuated).
| Age (years) | Severe |
Attenuated |
t-test |
||||
|---|---|---|---|---|---|---|---|
| n | Mean (kg) | SD | n | Mean (kg) | SD | p = | |
| At birth | 72 | 3.40 | 0.40 | 31 | 3.25 | 0.35 | 0.07259 |
| 1 month | 15 | 5.09 | 0.57 | 3 | 4.97 | 0.59 | 0.76747 |
| 3.5 month | 59 | 7.83 | 0.97 | 21 | 7.39 | 0.71 | 0.03266 |
| 6.5 month | 48 | 9.41 | 1.05 | 18 | 9.02 | 0.45 | 0.03629 |
| 9.5 month | 42 | 10.61 | 1.14 | 13 | 9.94 | 0.78 | 0.02298 |
| 1 y | 46 | 11.86 | 1.35 | 16 | 10.99 | 1.15 | 0.01767 |
| 1.5 y | 61 | 13.48 | 1.76 | 17 | 12.54 | 1.14 | 0.07379 |
| 2 y | 41 | 15.58 | 2.09 | 13 | 14.16 | 1.62 | 0.01699 |
| 2.5 y | 5 | 19.02 | 3.55 | 0 | N/A | N/A | N/A |
| 3 y | 47 | 19.01 | 2.88 | 18 | 15.55 | 1.67 | 0.00000 |
| 4 y | 26 | 20.84 | 3.65 | 13 | 17.50 | 2.13 | 0.00094 |
| 5 y | 17 | 23.23 | 3.72 | 9 | 19.60 | 1.85 | 0.00286 |
| 6 y | 20 | 27.69 | 6.16 | 12 | 21.54 | 2.47 | 0.00048 |
| 7 y | 10 | 26.21 | 4.30 | 4 | 22.45 | 3.45 | 0.13056 |
| 8 y | 12 | 35.31 | 10.42 | 10 | 24.18 | 2.33 | 0.00354 |
| 9 y | 2 | 26.50 | 3.54 | 4 | 25.08 | 4.82 | 0.71003 |
| 10 y | 11 | 30.70 | 6.22 | 7 | 26.24 | 4.59 | 0.10137 |
| 11 y | 1 | 29.00 | N/A | 2 | 27.90 | 1.27 | N/A |
| 12 y | 8 | 30.86 | 3.50 | 5 | 28.70 | 4.67 | 0.40451 |
| 13 y | 2 | 28.00 | 0.00 | 2 | 32.70 | 1.84 | 0.17179 |
| 14 y | 8 | 29.66 | 6.42 | 2 | 36.55 | 4.88 | 0.23703 |
| 15 y | 3 | 26.33 | 8.14 | 3 | 32.93 | 9.72 | 0.41968 |
| 16 y | 4 | 31.39 | 6.31 | 3 | 36.80 | 6.20 | 0.31351 |
| 18 y | 4 | 28.10 | 1.36 | 12 | 40.20 | 7.96 | 0.00024 |