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. 2014 Jun 17;11(6):e1001664. doi: 10.1371/journal.pmed.1001664

Table 8. Vascular occlusive events (fatal and non-fatal) by category of predicted risk of death and red blood cell transfusion.

Predicted Risk of Deatha Vascular Occlusive Events according to Transfusion Status of Patient OR (95% CI) Risk Difference (95% CI) p-Value
Transfusion No Transfusion
<6% 50/3,406 (1.5%) 16/5,300 (0.3%) 4.92 (2.80 to 8.65) 1.2% (0.7% to 1.6%) <0.0001
6%–20% 81/3,905 (2.1%) 37/2,945 (1.3%) 1.66 (1.13 to 2.46) 0.8% (0.2% to 1.4%) 0.009
21%–50% 84/1,761 (4.8%) 27/997 (2.7%) 1.80 (1.16 to 2.80) 2.1% (0.6% to 3.5%) 0.006
>50% 51/960 (5.3%) 20/583 (3.4%) 1.58 (0.93 to 2.68) 1.9% (−0.2% to 3.9%) 0.081

Interaction between RBC transfusion and predicted risk of death on the OR, p = 0.013.

a

Risk group determined according to model published in [10].