Table 1. Clinical features and hemodynamic parameters of patients.
| Carriers of mutations | Non-carriers of mutations | p-value | Idiopathic PAH | Associated PAH | p-value | |
| Number | 20 | 21 | 16 | 25 | ||
| Gender | 10 F/10 M | 10 F/11 M | 0.216 | 8 F/8 M | 13 F/12 M | 0.552 |
| Age at diagnosis (years) | 53±15 | 51±16 | 0.437 | 52±21 | 53±12 | 0.552 |
| mPaP (mmHg) | 57±15 | 45±14 | 0.043 | 52±16 | 47±13 | 0.510 |
| sPaP (mmHg) | 69±22 | 73±19 | 0.448 | 74±20 | 70±21 | 0.490 |
| PVR (mmHg.l − 1 .m − 1 ) | 11.92±3.18 | 8.53±4.46 | 0.043 | 9.96±4.68 | 7.21±2.8 | 0.222 |
| CI (l.m − 1 .m − 2 ) | 2.05±0.68 | 3.75±0.44 | 0.040 | 2.6±0.74 | 2.54±0.45 | 0.346 |
| 6MWT (m) | 314±130 | 428±103 | 0.020 | 370±136 | 374±127 | 0.308 |
| PAH types | 10 IPAH/10 APAH | 6 IPAH/15 APAH | 0,222 | 16 patients | 25 patients | 0,222 |
Values are expressed as mean ± standard deviation; F: female, M: male; mPaP: mean pulmonary artery pressure; sPaP: systolic pulmonary artery pressure; PVR: pulmonary vascular resistence; CI: cardiac index; 6MWT: 6 minute walking test; IPAH: idiopathic pulmonary arterial hypertension; APAH: associated pulmonary arterial hypertension.