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. 2014 Jun 17;9(6):e100118. doi: 10.1371/journal.pone.0100118

Table 4. Unadjusted and adjusted odds ratios (ORs) with 95% confidence intervals (CIs) of having low muscle mass only, visceral obesity only and combined low muscle mass and visceral obesity by quartiles of CRF (mL/kg/min) adjusting for potential compounding factors.

Quartiles of CRF (mL/kg/min)
Low muscle mass Q4 (highest) Q3 Q2 Q1 (lowest) P for trend
Unadjusted 1 1.55 (0.79, 3.07) 2.47 (1.26, 4.85) 4.82 (2.40, 9.68) <0.001
Model 1 1 1.63 (0.80, 3.33) 2.58 (1.25, 5.33) 4.58 (2.09, 10.02) <0.001
Model 2 1 2.03 (0.93, 4.45) 2.90 (1.30, 6.45) 5.55 (2.35, 13.12) <0.001
Model 3 1 1.80 (0.75, 4.35) 2.06 (0.86, 4.96) 4.98 (1.91, 12.99) 0.001
Visceral Obesity
Unadjusted 1 1.87 (0.81, 4.30) 2.74 (1.23, 6.11) 3.70 (1.67, 8.21) 0.001
Model 1 1 2.12 (0.86, 5.22) 3.49 (1.42, 8.56) 4.60 (1.80, 11.74) 0.001
Model 2 1 2.08 (0.68, 6.40) 4.18 (1.43, 12.24) 5.36 (1.69, 17.01) 0.002
Model 3 1 2.10 (0.52, 8.40) 4.26 (1.11, 16.41) 6.48 (1.56, 26.89) 0.004
Combined low muscle mass and visceral obesity
Unadjusted 1 2.07 (0.78, 5.53) 2.23 (0.84, 5.89) 3.74 (1.47, 9.50) 0.006
Model 1 1 2.36 (0.82, 6.80) 2.99 (1.02, 8.74) 5.99 (1.97, 18.18) 0.002
Model 2 1 3.60 (0.97, 13.33) 4.69 (1.29, 16.98) 10.54 (2.66 41.73) 0.001
Model 3 1 7.63 (1.18, 49.47) 7.50 (1.19, 47.45) 31.46 (4.31, 229.68) 0.001

Model 1: adjusted for age and sex.

Model 2: adjusted for age, sex, smoking status, and alcohol consumption, systolic and diastolic blood pressure, total cholesterol, HDL-cholesterol, triglycerides, fasting plasma glucose.

Model 3: adjusted for age, sex, smoking status, and alcohol consumption, systolic and diastolic blood pressure, total cholesterol, HDL-cholesterol, triglycerides, fasting plasma glucose, HOMA-IR, hsCRP, interleukin-6, TNF-α, and leptin.