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. Author manuscript; available in PMC: 2014 Jun 17.
Published in final edited form as: Cancer. 2010 Oct 19;117(6):1236–1244. doi: 10.1002/cncr.25575

Table 1.

Dose Modifications During Induction Therapy

Dose
Level
Idarubicin
(mg/m2/d
× 3)
Cytarabine
(g/m2/24 h
× 3-4) days
Tipifarnib
(mg PO BID
× 21 d every
course)
0 12 1.5 300
−1 8 1.0 200
−2 6 0.75 100