Table 4.
Adverse Events in ≥5% of All Patients During Induction (Regardless of Causality)
| Adverse Events During Induction |
Any Grade |
Grade ≥3 |
|---|---|---|
| No. | No. | |
| Diarrhea | 68 | 33 |
| Nausea/vomiting | 56 | 9 |
| Rash/pruritis | 51 | 18 |
| Hepatic (bilirubin/SGPT) | 31 | 13 |
| Mucositis/stomatitis/colitis/gastritis | 29 | 10 |
| Pain | 28 | 5 |
| Fatigue | 20 | 7 |
| Neurologic (anxiety, mood alteration, seizure, vision) |
15 | 3 |
| Cardiac | 15 | 1 |
| Hypokalemia | 14 | 13 |
| Edema | 12 | 1 |
| Respiratory | 11 | 2 |
| Constipation | 11 | 0 |
| Hypoalbuminemia | 10 | 3 |
| Hyperglycemia | 10 | 2 |
| Hypophosphatemia | 8 | 6 |
| Anorexia/weight loss | 8 | 2 |
| Renal | 8 | 1 |
| Hypocalcemia | 6 | 2 |
| Hemorrhage/bleeding | 5 | 3 |