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. 2014 Jun 12;9:2891–2903. doi: 10.2147/IJN.S60661

Figure 8.

Figure 8

Effect of SiO2 particles on mitochondrial respiratory chain complexes I (A) and IV (B) in BRL cells after coculture.

Notes: BRL cells were incubated with the cell-free supernatant of KsB or Kupffer cells stimulated with SiO2 particles (NPKsB, MPKsB, 2.0 mg/mL) or lipopolysaccharide 1 μg/mL for 24 hours. The data are presented as the mean ± standard deviation of three independent experiments performed in triplicate. **P<0.01 compared with KsB.

Abbreviations: KsB, BRL cells treated with the supernatant from the untreated Kupffer cells; LKsB, BRL cells treated with the supernatant from the lipopolysaccharide-treated Kupffer cells; NPKsB, BRL cells treated with the supernatant from the SiO2 NP-treated Kupffer cells; MPKsB, BRL cells treated with the supernatant from the micrometer SiO2 particle-treated Kupffer cells; BRL, buffalo rat liver; NADH, nicotinamide adenine dinucleotide; Cyto C, cytochrome C.