Table 1.
Clinico-pathological features of mucosal melanomas
| Case | Name | Age, years | Sex, F/M | Localization | Symptoms | Type of tumor cells | Melanin | IHC | Observations |
|---|---|---|---|---|---|---|---|---|---|
| 1 | FS | 67 | M | Nasal cavity | Epistaxis | Epithelioid | +++ | NA | Smoker |
| 2 | MG | 74 | M | Nasal cavity | Epistaxis | Epithelioid | − | NA | Smoker |
| 3 | VD | 69 | M | Nasal cavity | Epistaxis | Epithelioid | − | + | Smoker |
| 4 | NN | 73 | F | Nasal cavity | Epistaxis | Epithelioid | − | NA | |
| 5 | RM | 68 | M | Oropharynx, larynx | Hoarseness, mild dyspnea, dysphagia, odynophagia | Epithelioid, spindle | +++ | − | Smoker |
| 6 | PT | 67 | F | Right mandibular gum | Gingival hyperplasia, bleeding | Epithelioid | − | NA | |
| 7 | SP | 53 | M | Right palatine tonsil | Tonsillar tumor, bleeding, anemia | Epithelioid | − | NA | Melena with lipothymia: gastric and ileal melanoma metastases, 2 LN: metastases Smoker |
| 8 | AM | 59 | M | Left jugal maxillary mucosa | Jugal polyp, bleeding | Epithelioid | − | NA | Smoker |
| 9 | BT | 94 | M | Lower lip | Bleeding | Epithelioid, spindle | + | NA | At diagnosis, metastases in three lymph nodes After 5 months, submandibular metastases Smoker |
| 10 | CE | 65 | F | Anus | Epithelioid | + | NA | The current presentation is a vaginal metastases after anal canal melanoma | |
| 11 | MI | 66 | M | Rectum | Rectal polyp | Epithelioid | + | NA | Smoker |
| 12 | UI | 58 | M | Ileum | Intestinal occlusion, fecal peritonitis | Epithelioid | − | + | In the resection specimen were identified four lymph nodes free of metastases Smoker |
| 13 | VM | 71 | F | Vulva | Burns at urination, bleeding | Epithelioid | − | + | |
| 14 | SV | 53 | F | Not assessed | Pelvic tumor | Epithelioid, spindle | − | + | Tumor included ovary and uterus Smoker |
| 15 | CE | 62 | F | Urethra | Burns at urination, tumor presence | Epithelioid | +++ | − | Four lymph nodes free of metastases |
| 16 | DZ | 73 | M | Retroperitoneum | Epithelioid | + | + | Smoker | |
| 17 | PR | 73 | F | Pleura | Epithelioid | + | − | Pleural metastases, unknown origin |
Abbreviations: F, female; M, male; IHC, immunohistochemistry; +, positive for melanocytic markers; —, negative for melanocytic markers; NA, not assessed; LN, lymph nodes.